Assay Detail
Functional
CHEMBL684575
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory effect on spasmogen (carbachol) induced contraction of guinea pig tracheal strips.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Trachea |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New bronchodilators. 1. 1,5-Substituted 1H-imidazo[4,5-c]quinolin-4(5H)-ones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.50 | 4.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL434802 | — | — | 1 | 4.57 |
| CHEMBL1370561 | AMINOPHYLLINE | 4.0 | 1 | 4.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL434802 | — | IC50 | = | 27200.0 | nM | 4.57 |
| CHEMBL1370561 | AMINOPHYLLINE | IC50 | = | 37700.0 | nM | 4.42 |