Assay Detail
Functional
CHEMBL684577
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory effect on spasmogen (leukotriene, LTD4) induced contraction of guinea pig tracheal strips.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Trachea |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New bronchodilators. 1. 1,5-Substituted 1H-imidazo[4,5-c]quinolin-4(5H)-ones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.84 | 5.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL434802 | — | — | 1 | 5.04 |
| CHEMBL1370561 | AMINOPHYLLINE | 4.0 | 1 | 4.63 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL434802 | — | IC50 | = | 9190.0 | nM | 5.04 |
| CHEMBL1370561 | AMINOPHYLLINE | IC50 | = | 23600.0 | nM | 4.63 |