Assay Detail

CHEMBL686349

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Effect on carbachol induced contraction of guinea pig tracheal strips

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Cavia porcellus (CHEMBL369) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Cavia porcellus (CHEMBL369) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Cavia porcellus

CHEMBL369

Anchored from Assay target.

Protein identity Cavia porcellus

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Cavia porcellus
Tissue	Trachea
Confidence	1 — Organism
Curated By	Expert

Target

Cavia porcellus (CHEMBL369) ↗

Type	ORGANISM
Organism	Cavia porcellus

Publication

New bronchodilators. 3. Imidazo[4,5-c][1,8]naphthyridin-4(5H)-ones.

Suzuki F, Kuroda T, Kawakita T, Manabe H, Kitamura S, Ohmori K, Ichimura M, Kase H, Ichikawa S.
J Med Chem (1992) 35 : 4866 -4874
PubMed 1479586 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	4.71	4.99

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL95509	—	—	1	4.99
CHEMBL1370561	AMINOPHYLLINE	4.0	1	4.42

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL95509	—	IC50	=	10200.0	nM	4.99
CHEMBL1370561	AMINOPHYLLINE	IC50	=	37700.0	nM	4.42