Assay Detail

CHEMBL686664

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Functional

Compound was tested in vivo for the inhibition of serotonin release in rat peritoneal cell

ChEMBL ↗

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Target

Cavia porcellus (CHEMBL369) ↗

Open DB target context

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Primary target Cavia porcellus

CHEMBL369

Anchored from Assay target.

Protein identity Cavia porcellus

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Cavia porcellus
Confidence	1 — Organism
Curated By	Intermediate

Target

Cavia porcellus (CHEMBL369) ↗

Type	ORGANISM
Organism	Cavia porcellus

Publication

Indolo[2,1-c][1,4]benzodiazepines: a new class of antiallergic agents.

Ho CY, Hageman WE, Persico FJ.
J Med Chem (1986) 29 : 1118 -1121
PubMed 2872333 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.70	4.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL13828	OXATOMIDE	2.0	1	4.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL13828	OXATOMIDE	IC50	=	20100.0	nM	4.70