Assay Detail
Functional
CHEMBL688430
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity in guinea pig ileum preparation
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Activities of morphinone and N-(cyclopropylmethyl)normorphinone at opioid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.35 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278086 | ETHYLKETAZOCINE | — | 1 | 8.80 |
| CHEMBL70 | MORPHINE | 4.0 | 1 | 7.10 |
| CHEMBL27465 | — | — | 1 | 6.97 |
| CHEMBL29772 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278086 | ETHYLKETAZOCINE | IC50 | = | 1.6 | nM | 8.80 |
| CHEMBL70 | MORPHINE | IC50 | = | 79.8 | nM | 7.10 |
| CHEMBL27465 | — | IC50 | = | 108.0 | nM | 6.97 |
| CHEMBL29772 | — | IC50 | = | 300.0 | nM | 6.52 |