Assay Detail
Functional
CHEMBL689674
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Evaluated for antihistamine action using guinea pig ilea
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
A study of novel antiallergic agents with eosinophilic infiltration inhibiting action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 8 | 6.89 | 7.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13828 | OXATOMIDE | 2.0 | 1 | 7.34 |
| CHEMBL539525 | — | — | 1 | 7.13 |
| CHEMBL538756 | — | — | 1 | 7.11 |
| CHEMBL542889 | — | — | 1 | 6.93 |
| CHEMBL543356 | — | — | 1 | 6.82 |
| CHEMBL544064 | — | — | 1 | 6.81 |
| CHEMBL545708 | — | — | 1 | 6.56 |
| CHEMBL538258 | — | — | 1 | 6.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13828 | OXATOMIDE | Kd | = | 45.71 | nM | 7.34 |
| CHEMBL539525 | — | Kd | = | 74.13 | nM | 7.13 |
| CHEMBL538756 | — | Kd | = | 77.62 | nM | 7.11 |
| CHEMBL542889 | — | Kd | = | 117.49 | nM | 6.93 |
| CHEMBL543356 | — | Kd | = | 151.36 | nM | 6.82 |
| CHEMBL544064 | — | Kd | = | 154.88 | nM | 6.81 |
| CHEMBL545708 | — | Kd | = | 275.42 | nM | 6.56 |
| CHEMBL538258 | — | Kd | = | 407.38 | nM | 6.39 |