Assay Detail
Functional
CHEMBL718156
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Effective concentration that causes twitch inhibition in a mouse vas deferens assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Vas deferens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 10 | 7.66 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL75591 | — | — | 1 | 8.52 |
| CHEMBL120526 | METHANANDAMIDE | — | 1 | 8.00 |
| CHEMBL429055 | — | — | 1 | 7.96 |
| CHEMBL122884 | — | — | 1 | 7.93 |
| CHEMBL120428 | — | — | 1 | 7.55 |
| CHEMBL121384 | — | — | 1 | 7.44 |
| CHEMBL330974 | — | — | 1 | 7.44 |
| CHEMBL15848 | ANANDAMIDE | — | 1 | 7.28 |
| CHEMBL120889 | — | — | 1 | 7.22 |
| CHEMBL123120 | — | — | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL75591 | — | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL120526 | METHANANDAMIDE | EC50 | = | 10.1 | nM | 8.00 |
| CHEMBL429055 | — | EC50 | = | 10.9 | nM | 7.96 |
| CHEMBL122884 | — | EC50 | = | 11.7 | nM | 7.93 |
| CHEMBL120428 | — | EC50 | = | 28.3 | nM | 7.55 |
| CHEMBL121384 | — | EC50 | = | 36.0 | nM | 7.44 |
| CHEMBL330974 | — | EC50 | = | 36.1 | nM | 7.44 |
| CHEMBL15848 | ANANDAMIDE | EC50 | = | 52.7 | nM | 7.28 |
| CHEMBL120889 | — | EC50 | = | 59.7 | nM | 7.22 |
| CHEMBL123120 | — | EC50 | = | 60.6 | nM | 7.22 |