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Compound Detail

CHEMBL121384

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CCCCCCC(C)(C)/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCOC

Basic Information

ChEMBL ID CHEMBL121384
Phase Preclinical
Structure Type MOL
InChI Key KDHDLCAGLCQLAO-RPHFINAJSA-N
2
Targets
3
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

417.7
MW (Da)
7.31
ALogP
2
HBA
1
HBD
38.3
PSA (Ų)
0.18
QED
1
Ro5 Violations
19
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C27H47NO2
MW 417.68
Aromatic Rings 0
Heavy Atoms 30
NP-Likeness 0.39

Activity Summary

Ki 2 meas. best 8.41
EC50 1 meas. best 7.44

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Cannabinoid receptor
CHEMBL2111385
Ki 8.41 7.84 3.9 2
Mus musculus
CHEMBL375
EC50 7.44 7.44 36.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
9357529 10.1021/jm9702950 Mus musculus 10
9357529 10.1021/jm9702950 Cannabinoid receptor 2

Data from ChEMBL 36 via Core Engine