Assay Detail
Functional
CHEMBL725221
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Inhibition of serotonin uptake carrier in mice
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.58 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL153036 | R-FLUOXETINE | — | 1 | 7.68 |
| CHEMBL1169388 | — | — | 1 | 7.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL153036 | R-FLUOXETINE | Ki | = | 21.0 | nM | 7.68 |
| CHEMBL1169388 | — | Ki | = | 33.0 | nM | 7.48 |