Assay Detail
Functional
CHEMBL741597
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Inhibitory activity against the production of interleukin 4 (IL-4)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Peptidic immunosuppressants from the fungus Trichoderma polysporum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.60 | 8.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL160 | CYCLOSPORINE | 4.0 | 1 | 8.60 |
| CHEMBL3142672 | — | — | 1 | - |
| CHEMBL3142673 | — | — | 1 | - |
| CHEMBL3142670 | — | — | 1 | - |
| CHEMBL3142671 | — | — | 1 | - |
| CHEMBL3142669 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL160 | CYCLOSPORINE | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL3142672 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL3142673 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL3142670 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL3142671 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL3142669 | — | IC50 | > | 1000.0 | nM | - |