Assay Detail
Binding
CHEMBL754442
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Affinity against the Opioid receptor delta 1
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
N-substituent modulation of opiate agonist/antagonist activity in resolved 3-methyl-3-(m-hydroxyphenyl)piperidines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 7.82 | 8.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL340032 | DADLE | — | 1 | 8.68 |
| CHEMBL149414 | — | — | 1 | 7.85 |
| CHEMBL80 | NALOXONE | 4.0 | 1 | 7.75 |
| CHEMBL1500 | DIHYDROMORPHINE | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL340032 | DADLE | Kd | = | 2.1 | nM | 8.68 |
| CHEMBL149414 | — | Kd | = | 14.0 | nM | 7.85 |
| CHEMBL80 | NALOXONE | Kd | = | 18.0 | nM | 7.75 |
| CHEMBL1500 | DIHYDROMORPHINE | Kd | = | 100.0 | nM | 7.00 |