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Assay Detail

CHEMBL756871

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was tested for the ability to displace delta-receptor specific radioligand [3H]DPDPE
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Delta-type opioid receptor (CHEMBL269)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Cyclic enkephalin analogues containing alpha-amino-beta-mercapto-beta,beta-pentamethylenepropionic acid at positions 2 or 5.
Bryan WM, Callahan JF, Codd EE, Lemieux C, Moore ML, Schiller PW, Walker RF, Huffman WF.
J Med Chem (1989) 32 : 302 -304
PubMed 2536436 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 8.09 9.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3084309 1 9.03
CHEMBL8234 ENKEPHALIN 1 8.82
CHEMBL2370369 1 6.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3084309 Ki = 0.94 nM 9.03
CHEMBL8234 ENKEPHALIN Ki = 1.5 nM 8.82
CHEMBL2370369 Ki = 387.0 nM 6.41