Assay Detail
Binding
CHEMBL758076
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist potency using GTP-gamma [35S]- binding assay for mu-opioid receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel C-terminus modifications of the Dmt-Tic motif: a new class of dipeptide analogues showing altered pharmacological profiles toward the opioid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.02 | 7.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL80463 | — | — | 1 | 7.73 |
| CHEMBL77001 | — | — | 1 | 7.43 |
| CHEMBL309307 | — | — | 1 | 6.96 |
| CHEMBL317956 | DELTORPHIN C | — | 1 | 5.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL80463 | — | EC50 | = | 18.8 | nM | 7.73 |
| CHEMBL77001 | — | EC50 | = | 37.1 | nM | 7.43 |
| CHEMBL309307 | — | EC50 | = | 109.0 | nM | 6.96 |
| CHEMBL317956 | DELTORPHIN C | EC50 | = | 1130.0 | nM | 5.95 |