Assay Detail
Binding
CHEMBL767652
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Tested for binding affinity against RNA construct C
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Intermediate |
Publication
Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.35 | 5.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2368770 | — | — | 1 | 5.41 |
| CHEMBL184618 | FRAMYCETIN | 3.0 | 1 | 5.36 |
| CHEMBL370143 | PAROMOMYCIN | 4.0 | 1 | 5.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2368770 | — | Kd | = | 3890.0 | nM | 5.41 |
| CHEMBL184618 | FRAMYCETIN | Kd | = | 4340.0 | nM | 5.36 |
| CHEMBL370143 | PAROMOMYCIN | Kd | = | 5330.0 | nM | 5.27 |