Assay Detail
Functional
CHEMBL768973
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Compound was tested in vitro for its ability to aggregate platelet-rich plasma (PRP) in rabbit
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structure-activity relationship in PAF-acether. 3. Hydrophobic contribution to agonistic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 6.30 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1788194 | — | — | 1 | 7.72 |
| CHEMBL17935 | PLATELET ACTIVATING FACTOR | — | 1 | 7.35 |
| CHEMBL12852 | — | — | 1 | 7.24 |
| CHEMBL167786 | — | — | 1 | 6.72 |
| CHEMBL168094 | — | — | 1 | 6.64 |
| CHEMBL349217 | — | — | 1 | 5.92 |
| CHEMBL165267 | — | — | 1 | 4.77 |
| CHEMBL165929 | — | — | 1 | 4.00 |
| CHEMBL167569 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1788194 | — | EC50 | = | 19.0 | nM | 7.72 |
| CHEMBL17935 | PLATELET ACTIVATING FACTOR | EC50 | = | 45.0 | nM | 7.35 |
| CHEMBL12852 | — | EC50 | = | 57.0 | nM | 7.24 |
| CHEMBL167786 | — | EC50 | = | 190.0 | nM | 6.72 |
| CHEMBL168094 | — | EC50 | = | 230.0 | nM | 6.64 |
| CHEMBL349217 | — | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL165267 | — | EC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL165929 | — | EC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL167569 | — | EC50 | > | 100000.0 | nM | - |