Compound Detail
CHEMBL349217
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Basic Information
| ChEMBL ID | CHEMBL349217 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IAKLXPLKBYMOFA-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
439.5
MW (Da)
3.28
ALogP
7
HBA
0
HBD
94.1
PSA (Ų)
0.13
QED
0
Ro5 Violations
19
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 8.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Oryctolagus cuniculus CHEMBL374 | EC50 | 8.07 | 6.995 | 8.5 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Oryctolagus cuniculus | EC50 | = | 8.5 | nM | 8.07 | Compound was tested in vitro for its ability to aggregate washed rabbit platelet... | 3572968 |
| Oryctolagus cuniculus | EC50 | = | 1200.0 | nM | 5.92 | Compound was tested in vitro for its ability to aggregate platelet-rich plasma (... | 3572968 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3572968 | 10.1021/jm00388a008 | Oryctolagus cuniculus | 3 |
| 3572968 | 10.1021/jm00388a008 | Cavia porcellus | 2 |
| 3572968 | 10.1021/jm00388a008 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine