Assay Detail
Functional
CHEMBL768974
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Compound was tested in vitro for its ability to aggregate washed rabbit platelets (WP)
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structure-activity relationship in PAF-acether. 3. Hydrophobic contribution to agonistic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 8.60 | 10.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1788194 | — | — | 1 | 10.24 |
| CHEMBL17935 | PLATELET ACTIVATING FACTOR | — | 1 | 9.70 |
| CHEMBL12852 | — | — | 1 | 9.66 |
| CHEMBL167786 | — | — | 1 | 9.48 |
| CHEMBL168094 | — | — | 1 | 9.35 |
| CHEMBL349217 | — | — | 1 | 8.07 |
| CHEMBL165267 | — | — | 1 | 6.51 |
| CHEMBL165929 | — | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1788194 | — | EC50 | = | 0.057 | nM | 10.24 |
| CHEMBL17935 | PLATELET ACTIVATING FACTOR | EC50 | = | 0.2 | nM | 9.70 |
| CHEMBL12852 | — | EC50 | = | 0.22 | nM | 9.66 |
| CHEMBL167786 | — | EC50 | = | 0.33 | nM | 9.48 |
| CHEMBL168094 | — | EC50 | = | 0.45 | nM | 9.35 |
| CHEMBL349217 | — | EC50 | = | 8.5 | nM | 8.07 |
| CHEMBL165267 | — | EC50 | = | 310.0 | nM | 6.51 |
| CHEMBL165929 | — | EC50 | = | 1800.0 | nM | 5.75 |