Assay Detail
Functional
CHEMBL770828
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its ability to release [Ca2+] from permeabilised rabbit platelets.
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
6-Deoxy-6-hydroxymethyl scyllo-inositol 1,2,4-trisphosphate: A potent agonist at the inositol 1,4,5-trisphosphate receptor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.18 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL279107 | INS(1,4,5)P3 | — | 2 | 6.40 |
| CHEMBL1160362 | — | — | 1 | 6.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL279107 | INS(1,4,5)P3 | EC50 | = | 400.0 | nM | 6.40 |
| CHEMBL1160362 | — | EC50 | = | 440.0 | nM | 6.36 |
| CHEMBL279107 | INS(1,4,5)P3 | EC50 | = | 1670.0 | nM | 5.78 |