Assay Detail
Binding
CHEMBL804721
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity towards Sigma opioid receptor type 1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Sigma non-opioid intracellular receptor 1 (CHEMBL287) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Mixture-based synthetic combinatorial libraries.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.23 | 7.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL121919 | 5,6,7,8-TETRAHYDROISOQUINOLINE | — | 1 | 7.25 |
| CHEMBL122334 | HYDANTOIN | — | 1 | 7.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL121919 | 5,6,7,8-TETRAHYDROISOQUINOLINE | IC50 | = | 56.0 | nM | 7.25 |
| CHEMBL122334 | HYDANTOIN | IC50 | = | 62.0 | nM | 7.21 |