Assay Detail
Binding
CHEMBL816433
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Tested for inhibitory activity against Taq DNA polymerase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Benzoindoloquinolines interact with DNA tetraplexes and inhibit telomerase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.67 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL274096 | — | — | 1 | 6.05 |
| CHEMBL276202 | — | — | 1 | 5.66 |
| CHEMBL274335 | — | — | 1 | 5.30 |
| CHEMBL10763 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL274096 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL276202 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL274335 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL10763 | — | IC50 | > | 10000.0 | nM | - |