Assay Detail
Functional
CHEMBL820899
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Compound was tested for antiviral activity against Herpes Simplex virus Type-2(MS) in vero cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiviral activity of 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]purines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.09 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | 5.60 |
| CHEMBL44568 | — | — | 1 | 5.44 |
| CHEMBL1540 | PENCICLOVIR | 4.0 | 1 | 5.19 |
| CHEMBL43608 | — | — | 1 | 5.00 |
| CHEMBL298431 | — | — | 1 | 4.82 |
| CHEMBL43901 | — | — | 1 | 4.51 |
| CHEMBL42992 | — | — | 1 | - |
| CHEMBL44081 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL44568 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL1540 | PENCICLOVIR | IC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL43608 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL298431 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL43901 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL42992 | — | IC50 | = | 236000.0 | nM | - |
| CHEMBL44081 | — | IC50 | = | 128000.0 | nM | - |