Assay Detail
Binding
CHEMBL872745
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Concentration required for the inhibition of HIV- 1 Tat-derived peptide binding to TAR RNA.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Inhibition of an HIV-1 Tat-derived peptide binding to TAR RNA by aminoglycoside antibiotics
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.14 | 6.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184618 | FRAMYCETIN | 3.0 | 1 | 6.04 |
| CHEMBL372795 | STREPTOMYCIN | 4.0 | 1 | 5.02 |
| CHEMBL6067485 | GENTAMICIN | 4.0 | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184618 | FRAMYCETIN | IC50 | = | 920.0 | nM | 6.04 |
| CHEMBL372795 | STREPTOMYCIN | IC50 | = | 9500.0 | nM | 5.02 |
| CHEMBL6067485 | GENTAMICIN | IC50 | = | 45000.0 | nM | 4.35 |