Assay Detail
Binding
CHEMBL884453
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Inhibition of specific binding of [3H]spiroperidol to Dopamine receptor D2 in rat striatal membranes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Subcellular | Membrane |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
N-(Iodopropenyl)-octahydrobenzo[f]- and -[g]quinolines: synthesis and adrenergic and dopaminergic activity studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.11 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL670 | TEPA | — | 1 | 6.66 |
| CHEMBL132304 | — | — | 1 | 6.31 |
| CHEMBL26736 | — | — | 1 | 6.16 |
| CHEMBL134273 | — | — | 1 | 5.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL670 | TEPA | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL132304 | — | IC50 | = | 490.0 | nM | 6.31 |
| CHEMBL26736 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL134273 | — | IC50 | = | 5110.0 | nM | 5.29 |