Assay Detail
Functional
CHEMBL891298
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Antiproliferative activity against human Jurkat cells
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Jurkat |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of OSW saponin analogs with modified sugar residues and their antiproliferative activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 7.47 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL395810 | — | — | 1 | 7.82 |
| CHEMBL234362 | — | — | 1 | 7.11 |
| CHEMBL234783 | — | — | 1 | - |
| CHEMBL438499 | — | — | 1 | - |
| CHEMBL435354 | — | — | 1 | - |
| CHEMBL234782 | — | — | 1 | - |
| CHEMBL394699 | — | — | 1 | - |
| CHEMBL234781 | — | — | 1 | - |
| CHEMBL428319 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL395810 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL234362 | — | IC50 | = | 78.0 | nM | 7.11 |
| CHEMBL234783 | — | IC50 | - | — | - | |
| CHEMBL438499 | — | IC50 | - | — | - | |
| CHEMBL435354 | — | IC50 | - | — | - | |
| CHEMBL234782 | — | IC50 | - | — | - | |
| CHEMBL394699 | — | IC50 | - | — | - | |
| CHEMBL234781 | — | IC50 | - | — | - | |
| CHEMBL428319 | — | IC50 | - | — | - |