Assay Detail
Binding
CHEMBL937557
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]mibolerone from rat androgen receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.91 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL726 | FLUPHENAZINE | 4.0 | 1 | 6.10 |
| CHEMBL1085 | ACETOPHENAZINE | 4.0 | 1 | 6.10 |
| CHEMBL251940 | PERICIAZINE | 2.0 | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL726 | FLUPHENAZINE | Ki | = | 800.0 | nM | 6.10 |
| CHEMBL1085 | ACETOPHENAZINE | Ki | = | 800.0 | nM | 6.10 |
| CHEMBL251940 | PERICIAZINE | Ki | = | 3000.0 | nM | 5.52 |