Assay Detail
Functional
CHEMBL939992
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Antiparasitic activity against Trypanosoma cruzi Y trypomastigotes
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel 1,3,4-thiadiazolium-2-phenylamine chlorides derived from natural piperine as trypanocidal agents: chemical and biological studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.18 | 5.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL110 | BENZNIDAZOLE | 4.0 | 1 | 5.18 |
| CHEMBL412134 | — | — | 1 | 5.17 |
| CHEMBL259133 | — | — | 1 | - |
| CHEMBL410718 | — | — | 1 | - |
| CHEMBL259304 | — | — | 1 | - |
| CHEMBL406412 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL110 | BENZNIDAZOLE | IC50 | = | 6610.0 | nM | 5.18 |
| CHEMBL412134 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL259133 | — | IC50 | - | — | - | |
| CHEMBL410718 | — | IC50 | - | — | - | |
| CHEMBL259304 | — | IC50 | - | — | - | |
| CHEMBL406412 | — | IC50 | - | — | - |