Assay Detail
Binding
CHEMBL940156
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Binding affinity to Pyrococcus horikoshii sodium-coupled aspartate transporter
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pyrococcus horikoshii |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 7 | 8.15 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL274323 | ASPARTIC ACID | 3.0 | 1 | 8.70 |
| CHEMBL29757 | D-ASPARTATE | 2.0 | 1 | 8.05 |
| CHEMBL1160508 | — | — | 1 | 7.70 |
| CHEMBL576 | SUCCINIC ACID | 3.0 | 1 | - |
| CHEMBL11298 | SERINE | 3.0 | 1 | - |
| CHEMBL76232 | D-GLUTAMATE | — | 1 | - |
| CHEMBL575060 | GLUTAMIC ACID | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL274323 | ASPARTIC ACID | Kd | = | 2.0 | nM | 8.70 |
| CHEMBL29757 | D-ASPARTATE | Kd | = | 9.0 | nM | 8.05 |
| CHEMBL1160508 | — | Kd | = | 20.0 | nM | 7.70 |
| CHEMBL576 | SUCCINIC ACID | Kd | = | 1450000.0 | nM | - |
| CHEMBL11298 | SERINE | Kd | = | 160000.0 | nM | - |
| CHEMBL76232 | D-GLUTAMATE | Kd | = | 162000.0 | nM | - |
| CHEMBL575060 | GLUTAMIC ACID | Kd | = | 122000.0 | nM | - |