Assay Detail
Binding
CHEMBL948075
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Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | GF62 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Total synthesis and evaluation of [18F]MHMZ.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.62 | 9.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL62919 | ALTANSERIN | 2.0 | 1 | 9.13 |
| CHEMBL74355 | VOLINANSERIN | 3.0 | 1 | 8.68 |
| CHEMBL402143 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL62919 | ALTANSERIN | Ki | = | 0.74 | nM | 9.13 |
| CHEMBL74355 | VOLINANSERIN | Ki | = | 2.1 | nM | 8.68 |
| CHEMBL402143 | — | Ki | = | 9.0 | nM | 8.05 |