Assay Detail
Functional
CHEMBL964536
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human M4Be cells after 96 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | M4Be |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
In vitro and in vivo anti-tumoral activities of imidazo[1,2-a]quinoxaline, imidazo[1,5-a]quinoxaline, and pyrazolo[1,5-a]quinoxaline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.03 | 5.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL488644 | — | — | 1 | 5.59 |
| CHEMBL1282 | IMIQUIMOD | 4.0 | 1 | 4.47 |
| CHEMBL549386 | FOTEMUSTINE | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL488644 | — | IC50 | = | 2580.0 | nM | 5.59 |
| CHEMBL1282 | IMIQUIMOD | IC50 | = | 33500.0 | nM | 4.47 |
| CHEMBL549386 | FOTEMUSTINE | IC50 | = | 326000.0 | nM | - |