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Assay Detail

CHEMBL983402

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Herbicidal activity in Spinacia oleracea assessed as inhibition of photosynthetic electron transport by decrease in oxygen evolution
26
Total Activities
26
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Spinacia oleracea
Confidence 1 — Organism
Curated By Autocuration

Target

Spinacia oleracea (CHEMBL612824)
Type ORGANISM
Organism Spinacia oleracea

Publication

Investigating biological activity spectrum for novel quinoline analogues 2: hydroxyquinolinecarboxamides with photosynthesis-inhibiting activity.
Musiol R, Tabak D, Niedbala H, Podeszwa B, Jampilek J, Kralova K, Dohnal J, Finster J, Mencel A, Polanski J.
Bioorg Med Chem (2008) 16 : 4490 -4499
PubMed 18342517 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 14 4.87 5.72
Activity 12 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL278489 DCMU 1 5.72
CHEMBL468190 1 5.14
CHEMBL468654 1 5.06
CHEMBL468011 1 4.80
CHEMBL468643 1 4.50
CHEMBL501819 1 4.02
CHEMBL467340 1 -
CHEMBL467339 1 -
CHEMBL511596 1 -
CHEMBL468980 1 -
CHEMBL468979 1 -
CHEMBL468978 1 -
CHEMBL468808 1 -
CHEMBL450187 1 -
CHEMBL469012 1 -
CHEMBL468838 1 -
CHEMBL446391 1 -
CHEMBL466543 1 -
CHEMBL467952 1 -
CHEMBL455308 1 -
CHEMBL513335 1 -
CHEMBL468961 1 -
CHEMBL468960 1 -
CHEMBL466130 1 -
CHEMBL512637 1 -
CHEMBL468382 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL278489 DCMU IC50 = 1900.0 nM 5.72
CHEMBL468190 IC50 = 7200.0 nM 5.14
CHEMBL468654 IC50 = 8700.0 nM 5.06
CHEMBL468011 IC50 = 16000.0 nM 4.80
CHEMBL468643 IC50 = 32000.0 nM 4.50
CHEMBL501819 IC50 = 95000.0 nM 4.02
CHEMBL467340 Activity - -
CHEMBL467339 Activity - -
CHEMBL511596 Activity - -
CHEMBL468980 Activity - -
CHEMBL468979 Activity - -
CHEMBL468978 Activity - -
CHEMBL468808 Activity - -
CHEMBL450187 Activity - -
CHEMBL469012 Activity - -
CHEMBL468838 Activity - -
CHEMBL446391 Activity - -
CHEMBL466543 IC50 = 833000.0 nM -
CHEMBL467952 Activity - -
CHEMBL455308 IC50 = 426000.0 nM -
CHEMBL513335 IC50 = 468000.0 nM -
CHEMBL468961 IC50 = 265000.0 nM -
CHEMBL468960 IC50 = 114000.0 nM -
CHEMBL466130 IC50 = 137000.0 nM -
CHEMBL512637 IC50 = 107000.0 nM -
CHEMBL468382 IC50 = 819000.0 nM -