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Assay Detail

CHEMBL983403

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Herbicidal activity against Chlorella vulgaris Beij assessed as decrease in chlorophyll content after 7 days
26
Total Activities
26
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Chlorella vulgaris
Confidence 1 — Organism
Curated By Autocuration

Target

Chlorella vulgaris (CHEMBL613342)
Type ORGANISM
Organism Chlorella vulgaris

Publication

Investigating biological activity spectrum for novel quinoline analogues 2: hydroxyquinolinecarboxamides with photosynthesis-inhibiting activity.
Musiol R, Tabak D, Niedbala H, Podeszwa B, Jampilek J, Kralova K, Dohnal J, Finster J, Mencel A, Polanski J.
Bioorg Med Chem (2008) 16 : 4490 -4499
PubMed 18342517 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 20 4.65 5.32
Activity 6 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL450187 1 5.32
CHEMBL466543 1 5.26
CHEMBL469012 1 5.14
CHEMBL278489 DCMU 1 5.14
CHEMBL468980 1 5.07
CHEMBL468190 1 4.96
CHEMBL468979 1 4.80
CHEMBL467952 1 4.76
CHEMBL468382 1 4.71
CHEMBL468961 1 4.62
CHEMBL468654 1 4.36
CHEMBL468978 1 4.11
CHEMBL468838 1 4.08
CHEMBL467339 1 4.03
CHEMBL513335 1 4.01
CHEMBL455308 1 4.00
CHEMBL467340 1 -
CHEMBL468011 1 -
CHEMBL468960 1 -
CHEMBL446391 1 -
CHEMBL511596 1 -
CHEMBL466130 1 -
CHEMBL512637 1 -
CHEMBL501819 1 -
CHEMBL468643 1 -
CHEMBL468808 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL450187 IC50 = 4800.0 nM 5.32
CHEMBL466543 IC50 = 5500.0 nM 5.26
CHEMBL469012 IC50 = 7200.0 nM 5.14
CHEMBL278489 DCMU IC50 = 7300.0 nM 5.14
CHEMBL468980 IC50 = 8500.0 nM 5.07
CHEMBL468190 IC50 = 10900.0 nM 4.96
CHEMBL468979 IC50 = 15900.0 nM 4.80
CHEMBL467952 IC50 = 17200.0 nM 4.76
CHEMBL468382 IC50 = 19500.0 nM 4.71
CHEMBL468961 IC50 = 23800.0 nM 4.62
CHEMBL468654 IC50 = 43600.0 nM 4.36
CHEMBL468978 IC50 = 77700.0 nM 4.11
CHEMBL468838 IC50 = 83300.0 nM 4.08
CHEMBL467339 IC50 = 93700.0 nM 4.03
CHEMBL513335 IC50 = 97200.0 nM 4.01
CHEMBL455308 IC50 = 100000.0 nM 4.00
CHEMBL467340 IC50 = 149000.0 nM -
CHEMBL468011 IC50 = 102500.0 nM -
CHEMBL468960 IC50 = 108600.0 nM -
CHEMBL446391 IC50 = 158000.0 nM -
CHEMBL511596 Activity - -
CHEMBL466130 Activity - -
CHEMBL512637 Activity - -
CHEMBL501819 Activity - -
CHEMBL468643 Activity - -
CHEMBL468808 Activity - -