Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1087992

PLATYPHYLLONE
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
O=C(CCc1ccc(O)cc1)C[C@@H](O)CCc1ccc(O)cc1

Basic Information

ChEMBL ID CHEMBL1087992
Name PLATYPHYLLONE
Phase Preclinical
Structure Type MOL
InChI Key ZBFSUZGUYFFWGY-SFHVURJKSA-N
3
Targets
4
Activities
2
Assay Types
0
PK Parameters
12
Publications
0
Known Names

Molecular Properties

314.4
MW (Da)
2.98
ALogP
4
HBA
3
HBD
77.8
PSA (Ų)
0.70
QED
0
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C19H22O4
MW 314.38
Aromatic Rings 2
Heavy Atoms 23
NP-Likeness 1.11

Activity Summary

IC50 3 meas. best 4.52
EC50 1 meas. best 4.52

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
RAW264.7
CHEMBL612557
IC50 4.52 4.425 30000.0 2
Influenza A virus
CHEMBL613740
EC50 4.52 4.52 29900.0 1
NON-PROTEIN TARGET
CHEMBL3879801
IC50 4.26 4.26 54900.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine