Compound Detail
CHEMBL1209417
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1209417 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SXAJUVAFMFFQDT-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
348.3
MW (Da)
1.57
ALogP
5
HBA
1
HBD
106.8
PSA (Ų)
0.56
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.97
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Trypanosoma cruzi CHEMBL368 | IC50 | 4.97 | 4.97 | 10800.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Trypanosoma cruzi | IC50 | = | 10800.0 | nM | 4.97 | Antitrypanosomal activity against Trypanosoma cruzi Tulahuen 2 epimastigotes | 20634064 |
| Trypanosoma cruzi | IC50 | = | 10800.0 | nM | 4.97 | Antimicrobial activity against benznidazole-resistant epimastigotes of Trypanoso... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20634064 | 10.1016/j.bmcl.2010.06.101 | Trypanosoma cruzi | 2 |
| - | 10.1007/s00044-013-0781-3 | Trypanosoma cruzi | 2 |
| 20634064 | 10.1016/j.bmcl.2010.06.101 | No relevant target | 1 |
| - | 10.1007/s00044-013-0781-3 | Mycobacterium tuberculosis | 1 |
Data from ChEMBL 36 via Core Engine