Compound Detail
CHEMBL1209651
TETRAMETHYLAMMONIUM Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1209651 |
| Name | TETRAMETHYLAMMONIUM |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OKIZCWYLBDKLSU-UHFFFAOYSA-M |
| Parent Compound | CHEMBL46486 |
| Active Moiety | CHEMBL46486 |
1
Targets
10
Activities
2
Assay Types
0
PK Parameters
11
Publications
0
Known Names
Molecular Properties
74.2
MW (Da)
0.32
ALogP
0
HBA
0
HBD
0.0
PSA (Ų)
0.36
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 6 meas. best 4.52
IC50 4 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| High affinity choline transporter 1 CHEMBL3013 | Ki | 4.52 | 4.52 | 30060.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| High affinity choline transporter 1 | Ki | = | 30060.76 | nM | 4.52 | Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synapto... | 20637607 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10688634 | - | Solute carrier family 22 member 1 | 3 |
| 20637607 | 10.1016/j.bmcl.2010.06.090 | High affinity choline transporter 1 | 1 |
| 11060354 | - | Solute carrier family 22 member 1 | 1 |
| 10454528 | - | Organic cation/carnitine transporter 2 | 1 |
| 9632645 | 10.1074/jbc.273.26.15971 | Solute carrier family 22 member 3 | 1 |
| 11758759 | 10.1023/a:1013070128668 | Solute carrier family 22 member 1 | 1 |
| 12240953 | 10.1023/a:1019870831174 | Solute carrier family 22 member 2 | 1 |
| 11758759 | 10.1023/a:1013070128668 | Solute carrier family 22 member 2 | 1 |
| 11502595 | 10.1152/ajprenal.2001.281.3.f454 | Solute carrier family 22 member 2 | 1 |
| 7990927 | 10.1038/372549a0 | Solute carrier family 22 member 1 | 1 |
| 9260930 | 10.1089/dna.1997.16.871 | Solute carrier family 22 member 2 | 1 |
Data from ChEMBL 36 via Core Engine