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Compound Detail

CHEMBL1327202

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O=C(NC(CO)Cc1ccc([N+](=O)[O-])cc1)C(Cl)Cl

Basic Information

ChEMBL ID CHEMBL1327202
Phase Preclinical
Structure Type MOL
InChI Key HYKZHDMASNZUKI-UHFFFAOYSA-N
1
Targets
6
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

307.1
MW (Da)
1.42
ALogP
4
HBA
2
HBD
92.5
PSA (Ų)
0.47
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C11H12Cl2N2O4
MW 307.13
Aromatic Rings 1
Heavy Atoms 19
NP-Likeness -0.44

Activity Summary

IC50 6 meas. best 5.42

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 5.42 5.1533 3820.0 6

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine