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Compound Detail

CHEMBL1333930

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O=[N+]([O-])c1nn(-c2ccc3c(c2)OCCO3)[n+]([O-])c1Nc1ccccc1

Basic Information

ChEMBL ID CHEMBL1333930
Phase Preclinical
Structure Type MOL
InChI Key FXHJIMQXQWJNSM-UHFFFAOYSA-N
1
Targets
5
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

355.3
MW (Da)
1.93
ALogP
8
HBA
1
HBD
118.4
PSA (Ų)
0.33
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C16H13N5O5
MW 355.31
Aromatic Rings 3
Heavy Atoms 26
NP-Likeness -1.42

Activity Summary

EC50 3 meas. best 7.05
IC50 2 meas. best 5.98

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 7.05 6.4567 90.0 3
Unchecked
CHEMBL612545
IC50 5.98 5.445 1050.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine