Compound Detail
CHEMBL1336298
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Basic Information
| ChEMBL ID | CHEMBL1336298 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MGOPMGNLLMSUQB-JXMROGBWSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
219.2
MW (Da)
1.52
ALogP
3
HBA
2
HBD
78.9
PSA (Ų)
0.60
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.06
IC50 1 meas. best 4.98
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Voltage-gated inwardly rectifying potassium channel KCNH2 CHEMBL240 | EC50 | 6.06 | 6.06 | 880.0 | 1 |
| Mitogen-activated protein kinase 10 CHEMBL2637 | IC50 | 4.98 | 4.98 | 10540.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Voltage-gated inwardly rectifying potassium channel KCNH2 | EC50 | = | 880.0 | nM | 6.06 | PUBCHEM_BIOASSAY: Confirmation Dose Response screen for compounds that protect h... | - |
| Mitogen-activated protein kinase 10 | IC50 | = | 10540.0 | nM | 4.98 | PUBCHEM_BIOASSAY: Dose response biochemical screening assay for inhibitors of c-... | - |
Data from ChEMBL 36 via Core Engine