Compound Detail
CHEMBL1340338
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Basic Information
| ChEMBL ID | CHEMBL1340338 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LRCOOSVSWFTQSZ-UHFFFAOYSA-N |
4
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
293.7
MW (Da)
2.04
ALogP
3
HBA
3
HBD
77.5
PSA (Ų)
0.70
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.53
IC50 2 meas. best 6.69
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Intestinal-type alkaline phosphatase CHEMBL3151 | IC50 | 6.69 | 6.69 | 206.0 | 1 |
| Alkaline phosphatase, tissue-nonspecific isozyme CHEMBL5979 | IC50 | 6.68 | 6.68 | 211.0 | 1 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 6.53 | 6.53 | 294.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 4.84 | 4.84 | 14339.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Intestinal-type alkaline phosphatase | IC50 | = | 206.0 | nM | 6.69 | PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits from a small molecule ... | - |
| Alkaline phosphatase, tissue-nonspecific isozyme | IC50 | = | 211.0 | nM | 6.68 | PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS inhibitors of Mouse Intesti... | - |
| Zinc finger protein mex-5 | EC50 | = | 294.0 | nM | 6.53 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 14339.0 | nM | 4.84 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Data from ChEMBL 36 via Core Engine