Compound Detail
CHEMBL1340834
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Basic Information
| ChEMBL ID | CHEMBL1340834 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WFLQWQMYORDWLX-WQRHYEAKSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
488.0
MW (Da)
6.33
ALogP
6
HBA
1
HBD
70.8
PSA (Ų)
0.25
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.86
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| SUMO-activating enzyme CHEMBL2095174 | IC50 | 5.86 | 5.35 | 1390.0 | 2 |
| G-protein coupled receptor 55 CHEMBL1075322 | IC50 | 5.35 | 5.35 | 4430.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| SUMO-activating enzyme | IC50 | = | 1390.0 | nM | 5.86 | PUBCHEM_BIOASSAY: AlphaScreen confirmatory assay for validation of inhibitors of... | - |
| G-protein coupled receptor 55 | IC50 | = | 4430.19 | nM | 5.35 | PUBCHEM_BIOASSAY: Image-Based HTS for Selective Antagonists for GPR55. (Class of... | - |
| SUMO-activating enzyme | IC50 | = | 14560.0 | nM | 4.84 | PUBCHEM_BIOASSAY: uHTS HTRF assay for identification of inhibitors of SUMOylatio... | - |
Data from ChEMBL 36 via Core Engine