Compound Detail
CHEMBL1356238
PYRITHIONE 💊 Approved Drug
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
💊 Approved Drug
Basic Information
| ChEMBL ID | CHEMBL1356238 |
| Name | PYRITHIONE |
| Phase | Approved |
| Structure Type | MOL |
| InChI Key | FGVVTMRZYROCTH-UHFFFAOYSA-N |
| Therapeutic | ✓ Yes |
8
Targets
12
Activities
3
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
127.2
MW (Da)
0.61
ALogP
2
HBA
1
HBD
26.9
PSA (Ų)
0.31
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| First Approval | 1986 |
| Availability | Discontinued |
| Chirality | Achiral |
Activity Summary
IC50 9 meas. best 7.3
Ki 2 meas. best 6.66
Kd 1 meas. best 5.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Replicase polyprotein 1ab CHEMBL4523582 | IC50 | 7.3 | 7.3 | 50.0 | 1 |
| Unchecked CHEMBL612545 | Ki | 6.66 | 6.66 | 217.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 6.04 | 6.04 | 908.0 | 1 |
| No relevant target CHEMBL2362975 | Kd | 5.3 | 5.3 | 5000.0 | 1 |
| Lysyl oxidase homolog 3 CHEMBL4105989 | IC50 | 4.92 | 4.92 | 12000.0 | 1 |
| Lysyl oxidase homolog 4 CHEMBL4295926 | IC50 | 4.82 | 4.82 | 15000.0 | 1 |
| Lysyl oxidase homolog 2 CHEMBL3714029 | IC50 | 4.75 | 4.75 | 18000.0 | 1 |
| Stromelysin-1 CHEMBL283 | IC50 | 4.7 | 4.58 | 20000.0 | 2 |
| Protein-lysine 6-oxidase CHEMBL2249 | IC50 | 4.48 | 4.48 | 33000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine