Compound Detail
CHEMBL1371202
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Basic Information
| ChEMBL ID | CHEMBL1371202 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OVKDKTRSYHUXNE-UHFFFAOYSA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
363.5
MW (Da)
5.92
ALogP
3
HBA
0
HBD
20.3
PSA (Ų)
0.54
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 4 meas. best 5.42
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Streptokinase A CHEMBL1293228 | EC50 | 5.42 | 5.1875 | 3778.0 | 4 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Streptokinase A | EC50 | = | 3778.0 | nM | 5.42 | PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Iden... | - |
| Streptokinase A | EC50 | = | 5597.0 | nM | 5.25 | PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response Follow up to Iden... | - |
| Streptokinase A | EC50 | = | 7602.0 | nM | 5.12 | PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response Follow up to Iden... | - |
| Streptokinase A | EC50 | = | 10867.0 | nM | 4.96 | PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response HTS to Identify I... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33065375 | 10.1016/j.ejmech.2020.112842 | HT-1080 | 1 |
Data from ChEMBL 36 via Core Engine