Compound Detail
CHEMBL138614
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL138614 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FRCVOKAWJJIJHQ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
164.2
MW (Da)
1.66
ALogP
2
HBA
1
HBD
15.3
PSA (Ų)
0.73
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 2 meas. best 6.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2B CHEMBL323 | Kd | 6.02 | 6.02 | 955.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2B | Kd | = | 954.99 | nM | 6.02 | Displacement of [3H]5-HT binding to serotonin receptor of rat fundus membranes | 6581313 |
| 5-hydroxytryptamine receptor 2B | Kd | = | 954.99 | nM | 6.02 | The binding affinity to 5-hydroxytryptamine 2B receptor of rat fundus | 7086824 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6581313 | 10.1021/jm00367a008 | 5-hydroxytryptamine receptor 2B | 1 |
| 7086824 | 10.1021/jm00343a013 | 5-hydroxytryptamine receptor 2B | 1 |
Data from ChEMBL 36 via Core Engine