Compound Detail
CHEMBL1386646
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Basic Information
| ChEMBL ID | CHEMBL1386646 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FBZBPTAIJMWJJO-UHFFFAOYSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
276.3
MW (Da)
1.52
ALogP
5
HBA
1
HBD
87.8
PSA (Ų)
0.67
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.83
IC50 1 meas. best 5.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 6.83 | 6.83 | 149.0 | 1 |
| Galanin receptor type 3 CHEMBL2731 | IC50 | 5.76 | 5.76 | 1723.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 149.0 | nM | 6.83 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Inhi... | - |
| Galanin receptor type 3 | IC50 | = | 1723.0 | nM | 5.76 | PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose res... | - |
Data from ChEMBL 36 via Core Engine