Compound Detail
CHEMBL1390056
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Basic Information
| ChEMBL ID | CHEMBL1390056 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DKOWSOMMUFZILP-UHFFFAOYSA-N |
3
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
316.4
MW (Da)
4.84
ALogP
4
HBA
0
HBD
43.6
PSA (Ų)
0.49
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.3
IC50 1 meas. best 5.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein CHEMBL3885546 | EC50 | 5.3 | 5.3 | 4970.0 | 1 |
| Ephrin type-A receptor 4 CHEMBL1293259 | IC50 | 5.21 | 5.21 | 6110.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 5.06 | 5.06 | 8720.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein | EC50 | = | 4970.0 | nM | 5.3 | PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for small molecule ago... | - |
| Ephrin type-A receptor 4 | IC50 | = | 6110.0 | nM | 5.21 | PUBCHEM_BIOASSAY: Colorimetric assay for HTS discovery of chemical inhibitors of... | - |
| Unchecked | EC50 | = | 8720.0 | nM | 5.06 | PUBCHEM_BIOASSAY: HCS for Compounds that Up-Regulate Insulin Promoter Activity i... | - |
Data from ChEMBL 36 via Core Engine