Compound Detail
CHEMBL1414746
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Basic Information
| ChEMBL ID | CHEMBL1414746 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FCZJCOKJUMNOES-UHFFFAOYSA-N |
| Parent Compound | CHEMBL1620214 |
| Active Moiety | CHEMBL1620214 |
3
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
313.3
MW (Da)
2.91
ALogP
5
HBA
2
HBD
93.3
PSA (Ų)
0.57
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 5.36
IC50 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 5.36 | 5.36 | 4343.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 5.24 | 5.24 | 5817.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 4.47 | 4.47 | 34123.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Zinc finger protein mex-5 | EC50 | = | 4343.0 | nM | 5.36 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 5817.0 | nM | 5.24 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Unchecked | EC50 | = | 34123.0 | nM | 4.47 | PUBCHEM_BIOASSAY: Luminescence-based Microorganism Dose Response HTS to Identify... | - |
Data from ChEMBL 36 via Core Engine