Compound Detail
CHEMBL1425966
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Basic Information
| ChEMBL ID | CHEMBL1425966 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FKDCKFZJYVRFTF-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
355.4
MW (Da)
2.16
ALogP
7
HBA
1
HBD
107.4
PSA (Ų)
0.33
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Female germline-specific tumor suppressor gld-1 CHEMBL1293302 | IC50 | 5.4 | 5.4 | 3962.0 | 1 |
| Protein Rev CHEMBL1293282 | IC50 | 5.0 | 5.0 | 10098.0 | 1 |
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 4.48 | 4.48 | 33300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Female germline-specific tumor suppressor gld-1 | IC50 | = | 3962.0 | nM | 5.4 | PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput do... | - |
| Protein Rev | IC50 | = | 10098.0 | nM | 5.0 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of gld-1: Fluorescence polarizati... | - |
| Polyadenylate-binding protein 1 | IC50 | = | 33300.0 | nM | 4.48 | PUBCHEM_BIOASSAY: Dose-response confirmation of microRNA-mediated mRNA deacetyla... | - |
Data from ChEMBL 36 via Core Engine