Compound Detail
CHEMBL1429797
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Basic Information
| ChEMBL ID | CHEMBL1429797 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XJXYLZFUETZNSH-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
217.3
MW (Da)
3.82
ALogP
3
HBA
1
HBD
32.6
PSA (Ų)
0.72
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.12 | 5.12 | 7550.0 | 1 |
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 4.45 | 4.34 | 35200.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 7550.0 | nM | 5.12 | PUBCHEM_BIOASSAY: A biochemical assay using the ADP-Hunter methodology, purified... | - |
| Polyadenylate-binding protein 1 | IC50 | = | 35200.0 | nM | 4.45 | PUBCHEM_BIOASSAY: Dose-response secondary confirmation of microRNA-mediated mRNA... | - |
| Polyadenylate-binding protein 1 | IC50 | = | 59000.0 | nM | 4.23 | PUBCHEM_BIOASSAY: Dose-response confirmation of microRNA-mediated mRNA deacetyla... | - |
Data from ChEMBL 36 via Core Engine