Compound Detail
CHEMBL1448972
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Basic Information
| ChEMBL ID | CHEMBL1448972 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JNOKWPYVPIQTQD-OQLLNIDSSA-N |
2
Targets
6
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
341.3
MW (Da)
3.73
ALogP
5
HBA
0
HBD
57.1
PSA (Ų)
0.61
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 6 meas. best 6.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 6.9 | 5.602 | 127.0 | 5 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 4.22 | 4.22 | 60237.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 127.0 | nM | 6.9 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Acti... | - |
| Unchecked | EC50 | = | 901.0 | nM | 6.04 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Retest to Confirm Activators of 5... | - |
| Unchecked | EC50 | = | 2065.0 | nM | 5.68 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Activato... | - |
| Unchecked | EC50 | = | 10274.0 | nM | 4.99 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Activato... | - |
| Unchecked | EC50 | = | 39606.0 | nM | 4.4 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Activato... | - |
| RNA-binding protein pos-1 | EC50 | = | 60237.0 | nM | 4.22 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Data from ChEMBL 36 via Core Engine