Compound Detail
CHEMBL1452945
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Basic Information
| ChEMBL ID | CHEMBL1452945 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KGISDRAVHYRWIC-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
410.4
MW (Da)
4.23
ALogP
7
HBA
1
HBD
92.9
PSA (Ų)
0.61
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 5.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 5.89 | 5.89 | 1273.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 5.85 | 5.85 | 1411.0 | 1 |
| Endoribonuclease toxin MazF CHEMBL1795096 | EC50 | 4.77 | 4.77 | 16900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Zinc finger protein mex-5 | EC50 | = | 1273.0 | nM | 5.89 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 1411.0 | nM | 5.85 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Endoribonuclease toxin MazF | EC50 | = | 16900.0 | nM | 4.77 | PUBCHEM_BIOASSAY: Dose response confirmation uHTS hits for MazEF TA System activ... | - |
Data from ChEMBL 36 via Core Engine