Compound Detail
CHEMBL1487918
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Basic Information
| ChEMBL ID | CHEMBL1487918 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YOLRNVSNNJRUDP-UHFFFAOYSA-N |
4
Targets
5
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
384.3
MW (Da)
3.35
ALogP
5
HBA
1
HBD
100.6
PSA (Ų)
0.80
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 4 meas. best 4.92
IC50 1 meas. best 4.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| G-protein coupled receptor 35 CHEMBL1293267 | IC50 | 4.92 | 4.92 | 12010.5 | 1 |
| Unchecked CHEMBL612545 | EC50 | 4.92 | 4.92 | 11900.0 | 2 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 4.87 | 4.87 | 13484.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 4.84 | 4.84 | 14403.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 11900.0 | nM | 4.92 | PUBCHEM_BIOASSAY: Counterscreen for Fluorescence in GFP-Spectra Wavelengths Caus... | - |
| Unchecked | EC50 | = | 11900.0 | nM | 4.92 | PUBCHEM_BIOASSAY: HCS for Compounds that Up-Regulate Insulin Promoter Activity i... | - |
| G-protein coupled receptor 35 | IC50 | = | 12010.47 | nM | 4.92 | PUBCHEM_BIOASSAY: Image-Based HTS for Selective Antagonists of GPR35. High conte... | - |
| Zinc finger protein mex-5 | EC50 | = | 13484.0 | nM | 4.87 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 14403.0 | nM | 4.84 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Data from ChEMBL 36 via Core Engine